Product Information
85734-1-PBS targets DNALI1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | DNALI1 fusion protein Ag11652 Predict reactive species |
Full Name | dynein, axonemal, light intermediate chain 1 |
Calculated Molecular Weight | 258 aa, 30 kDa |
Observed Molecular Weight | 30-33 kDa |
GenBank Accession Number | BC046117 |
Gene Symbol | DNALI1 |
Gene ID (NCBI) | 7802 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | O14645 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
DNALI1 belongs to the inner dynein arm light chain family and encodes a subunit of the light intermediate chain of inner dynein arms of the axoneme of sperm flagella (PMID: 36792588). DNALI1 promotes neurodegeneration after traumatic brain injury via inhibition of autophagosome-lysosome fusion (PMID: 38348540). Mutation in DNALI1 Causes Male Infertility with Severe Oligoasthenoteratozoospermia in Humans (PMID: 38212584).