DUSP16 Polyclonal antibody

DUSP16 Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 14237-1-AP


DUSP16, KIAA1700, MAP kinase phosphatase 7, MKP 7, MKP7

Tested Applications

Positive WB detected inPC-12 cells, COLO 320 cells, HeLa cells, mouse brain tissue
Positive IHC detected inhuman colon tissue, human breast cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

14237-1-AP targets DUSP16 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen DUSP16 fusion protein Ag5479
Full Name dual specificity phosphatase 16
Calculated Molecular Weight 73 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberBC042101
Gene Symbol DUSP16
Gene ID (NCBI) 80824
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

DUSP16, also known as MKP-7, is a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. DUSP16 dephosphorylates JUN kinases (JNKs) specifically and thereby regulates T-cell differentiation, which can be responsible for the pathogenesis of Burkitt's lymphoma and cerebral ischemia. DUSP16 was also found to induce the expression of VCAM-1 through the suppression of JNK signaling.


Product Specific Protocols
WB protocol for DUSP16 antibody 14237-1-APDownload protocol
IHC protocol for DUSP16 antibody 14237-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Cell Death Discov

NR4A1 enhances MKP7 expression to diminish JNK activation induced by ROS or ER-stress in pancreatic β cells for surviving.

Authors - Ze-Qing Pu

Int Immunopharmacol

Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells

Authors - Qilin Feng

J Mol Cell Cardiol

Deficiency of smooth muscle cell ILF3 alleviates intimal hyperplasia via HMGB1 mRNA degradation-mediated regulation of the STAT3/DUSP16 axis

Authors - Ya-Min Hou

Int J Hyperthermia

Deregulated JNK signaling enhances apoptosis during hyperthermia

Authors - Atsushi Enomoto