DYX1C1 Polyclonal antibody, PBS Only

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• DYX1C1 Polyclonal antibody, PBS Only (14522-1-PBS)

• 

  WB analysis using 14522-1-AP (same clone as 14522-1-PBS)

  rat testis tissue were subjected to SDS PAGE followed by western blot with 14522-1-AP (DYX1C1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14522-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse testis using 14522-1-AP (same clone as 14522-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 14522-1-AP (DYX1C1 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14522-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rat testis using 14522-1-AP (same clone as 14522-1-PBS)

  rat testis tissue were subjected to SDS PAGE followed by western blot with 14522-1-AP (DYX1C1 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14522-1-PBS in a different storage buffer formulation.

• 

  IP experiment of mouse testis using 14522-1-AP (same clone as 14522-1-PBS)

  IP result of anti-DYX1C1 (IP:14522-1-AP, 4ug; Detection:14522-1-AP 1:800) with mouse testis tissue lysate 1120 ug. This data was developed using the same antibody clone with 14522-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

DYX1C1 Polyclonal Antibody for WB, IP, Indirect ELISA

Cat No. 14522-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, Indirect ELISA

Synonyms

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Product Information

14522-1-PBS targets DYX1C1 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag5997

  Product name: Recombinant human DYX1C1 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 1-381 aa of BC062564

  Sequence: MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDESSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEGRKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAVCHLKLKNLHKAIEDSSKEFCSLEGIECQASEPKLSHHIPSDLHVYIQMA

• Full Name: dyslexia susceptibility 1 candidate 1
• Calculated Molecular Weight: 49 kDa
• Observed Molecular Weight: 48 kDa
• GenBank Accession Number: BC062564
• Gene Symbol: DYX1C1
• Gene ID (NCBI): 161582
• RRID: AB_2093955
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q8WXU2
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

DYX1C1 initially was described as the first candidate gene for developmental dyslexia. The protein contains three TPR motifs and one p23 domain, all commonly known for their protein-protein interactions. It also has been linked to neuronal migration. Recently it has been reported that the expression of DYX1C1 protein is lost in breast cancer and patients who have lost DYX1C1 expression have a poor overall survival,indicating that DYX1C1 is a potential prognostic biomarker in breast cancer.