Dematin Polyclonal antibody, PBS Only

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• Dematin Polyclonal antibody, PBS Only (16808-1-PBS)

• 

  WB analysis using 16808-1-AP (same clone as 16808-1-PBS)

  human red blood cells were subjected to SDS PAGE followed by western blot with 16808-1-AP (Dematin antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16808-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rat brain using 16808-1-AP (same clone as 16808-1-PBS)

  rat brain tissue were subjected to SDS PAGE followed by western blot with 16808-1-AP (Dematin antibody at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16808-1-PBS in a different storage buffer formulation.

Dematin Polyclonal Antibody for WB, Indirect ELISA

Cat No. 16808-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

EPB49, EPB 49, DMTN, Dematin actin-binding protein

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Product Information

16808-1-PBS targets Dematin in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag10300

  Product name: Recombinant human EPB49 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 1-405 aa of BC017445

  Sequence: MERLQKQPLTSPGSVSPSRDSSVPGSPSSIVAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIYEPHFTYSLLEHVELPRSRERSLSPKSTSPPPSPEVWADSRSPGIISQASAPRTTGTPRTSLPHFHHPETSRPDSNIYKKPPIYKQRESVGGSPQTKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRKRKASRRGAEEEEEEEDDDSGEEMKALRERQREELSKVTSNLGKMILKEEMEKSLPIRRKTRSLPDRTPFHTSLHQGTSKSSSLPAYGRTTLSRLQSTEFSPSGSETGSPGLQNGEGQRGRMDRGNSLPCVLEQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF

• Full Name: erythrocyte membrane protein band 4.9 (dematin)
• Calculated Molecular Weight: 405 aa, 46 kDa
• Observed Molecular Weight: 48-52 kDa
• GenBank Accession Number: BC017445
• Gene Symbol: Dematin
• Gene ID (NCBI): 2039
• RRID: AB_2277891
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q08495
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Dematin (band 4.9) is a widely expressed cytoskeletal protein which regulates cell shape and cell migration. It is best known for its role within the red blood cell (RBC), where it has been localized to the spectrin-actin junctions of RBC membrane. Dematin has a 48 kDa subunit containing a headpiece domain and a 52 kDa subunit.