Endothelin 1 Polyclonal antibody
Endothelin 1 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
WB, IP, IHC, IF, ELISA
Cat no : 12191-1-AP
|Positive WB detected in||NIH/3T3 cells|
|Western Blot (WB)||WB : 1:200-1:1000|
|Sample-dependent, check data in validation data gallery|
|KD/KO||See 1 publications below|
|WB||See 12 publications below|
|IHC||See 1 publications below|
|IF||See 1 publications below|
|IP||See 1 publications below|
12191-1-AP targets Endothelin 1 in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
|Tested Reactivity||human, mouse|
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Endothelin 1 fusion protein Ag2847|
|Full Name||endothelin 1|
|Calculated molecular weight||212 aa, 24 kDa|
|Observed molecular weight||24 kDa|
|GenBank accession number||BC009720|
|Gene ID (NCBI)||1906|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
EDN1, also named as Endothelin-1, PPET1 and ET-1, belongs to the endothelin/sarafotoxin family. Endothelins are endothelium-derived vasoconstrictor peptides. Emerging basic science, and animal and human data all suggest that EDN1 is a potentially important contributor in the pathobiology of fibrosing disorders, including those that affect the lung(PMID:20055532 ).
|Product Specific Protocols|
|WB protocol for Endothelin 1 antibody 12191-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Lactoferrin-endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes.
Blocking mitochondrial cyclophilin D ameliorates TSH-impaired defensive barrier of artery.
Int J Biol Sci
Roquin2 suppresses breast cancer progression by inhibiting tumor angiogenesis via selectively destabilizing proangiogenic factors mRNA.
Cancer Gene Ther
Systems analysis identifies endothelin 1 axis blockade for enhancing the anti-tumor effect of multikinase inhibitor.
J Cell Mol Med
Macrophage-derived exosomal miR-4532 promotes endothelial cells injury by targeting SP1 and NF-κB P65 signalling activation
The lncRNA MALAT1 participates in regulating coronary slow flow endothelial dysfunction through the miR-181b-5p-MEF2A-ET-1 axis.