Endothelin 1 Monoclonal antibody
Endothelin 1 Monoclonal Antibody for FC, WB, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human and More (1)
Applications
WB, FC, ELISA
Conjugate
Unconjugated
CloneNo.
2C5B3
Cat no : 67008-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | human placenta tissue |
Positive FC detected in | HEK-293T cells |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:1000-1:4000 |
Sample-dependent, check data in validation data gallery |
Published Applications
WB | See 2 publications below |
Product Information
67008-1-Ig targets Endothelin 1 in WB, FC, ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Cited Reactivity | human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | Endothelin 1 fusion protein Ag28334 |
Full Name | endothelin 1 |
Calculated molecular weight | 212 aa, 24 kDa |
Observed molecular weight | 24 kDa |
GenBank accession number | BC009720 |
Gene symbol | EDN1 |
Gene ID (NCBI) | 1906 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
EDN1, also named as Endothelin-1, PPET1 and ET-1, belongs to the endothelin/sarafotoxin family. Endothelins are endothelium-derived vasoconstrictor peptides. Emerging basic science, and animal and human data all suggest that EDN1 is a potentially important contributor in the pathobiology of fibrosing disorders, including those that affect the lung(PMID:20055532 ).
Protocols
Product Specific Protocols | |
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WB protocol for Endothelin 1 antibody 67008-1-Ig | Download protocol |
FC protocol for Endothelin 1 antibody 67008-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Biomed Rep Cilostazol regulates the expressions of endothelin-1 and endothelial nitric oxide synthase via activation of the p38 MAPK signaling pathway in HUVECs | ||
Hypertens Res Endothelial-derived complement factor D contributes to endothelial dysfunction in malignant nephrosclerosis via local complement activation |