EHMT1 Polyclonal antibody, PBS Only

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• EHMT1 Polyclonal antibody, PBS Only (55436-1-PBS)

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  IP experiment of K-562 using 55436-1-AP (same clone as 55436-1-PBS)

  IP result of anti-EHMT1 (IP:55436-1-AP, 4ug; Detection:55436-1-AP 1:500) with K-562 cells lysate 1360 ug. This data was developed using the same antibody clone with 55436-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 55436-1-AP (same clone as 55436-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HeLa cells using EHMT1 antibody (55436-1-AP) at dilution of 1:600 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-phalloidin (red). This data was developed using the same antibody clone with 55436-1-PBS in a different storage buffer formulation.

EHMT1 Polyclonal Antibody for IF/ICC, IP, Indirect ELISA

Cat No. 55436-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, IP, Indirect ELISA

Synonyms

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Product Information

55436-1-PBS targets EHMT1 in IF/ICC, IP, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: euchromatic histone-lysine N-methyltransferase 1
• Calculated Molecular Weight: 141 kDa
• Observed Molecular Weight: 150-170 kDa
• GenBank Accession Number: NM_024757
• Gene Symbol: EHMT1
• Gene ID (NCBI): 79813
• RRID: AB_3670252
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9H9B1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

EHMT1, also known as GLP (G9a-like protein), encodes a histone lysine methyltransferase that controls brown adipose cell fate, adaptive thermogenesis, and glucose homeostasis in vivo (PMID: 24196706). EHMTs, along with LSD1 (an H3K4 demethylase), are components of the REST complex, which silences neuronal pathway genes in non-neuronal cells. EHMT1 is mainly responsible for the monomethylation and dimethylation of histone H3 lysine 9 (H3K9), forming a heteromeric complex with EHMT2 (G9a) in euchromatin (PMID: 34214254, 37663929).