Validation Data Gallery
|Sample-dependent, check data in validation data gallery|
14507-1-AP targets ELK1 in WB,ELISA applications and shows reactivity with human samples.
|Host / Isotype||Rabbit / IgG|
|Immunogen||ELK1 fusion protein Ag5966|
|Full Name||ELK1, member of ETS oncogene family|
|Calculated molecular weight||45 kDa|
|GenBank accession number||BC056150|
|Gene ID (NCBI)||2002|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
E twenty-six (ETS)-like transcription factor 1, also known as ELK1, is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. It is targeted in the nucleus by three major MAP kinase pathways as well as the CaMKII pathway. phosphorylation of nuclear Elk1 enhances its ability to bind DNA at serum response elements and stimulate transcription of immediate early genes. Elk1 plays important roles in various contexts, including long-term memory formation, drug addiction, Alzheimer's disease, down syndrome, breast cancer, and depression. This antibody got an 62 kd band in western blotting maybe duo to its phosphorylation
MicroRNA-326 suppresses the proliferation, migration and invasion of cervical cancer cells by targeting ELK1.
Competitive regulation of IPO4 transcription by ELK1 and GABP.
Br J Pharmacol
L-Hcy-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinemia.