Tested Applications
| Positive FC detected in | HUVEC cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
98325-1-RR targets PROCR/EPCR/CD201 in FC applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Eg2339 Product name: Recombinant Human PROCR protein (rFc Tag) Source: mammalian cells-derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 18-210 aa of BC014451 Sequence: SQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGPDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELREFLEDTCVQYVQKHISAENTKGSQTSRSYTS Predict reactive species |
| Full Name | protein C receptor, endothelial (EPCR) |
| Calculated Molecular Weight | 238 aa, 27 kDa |
| GenBank Accession Number | BC014451 |
| Gene Symbol | PROCR |
| Gene ID (NCBI) | 10544 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q9UNN8 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2 - 8°C. Stable for one year after shipment. |
Background Information
EPCR (endothelial cell protein C receptor), also known as CD201, is a type 1 transmembrane protein that is primarily found on endothelial cells. It exhibits sequence and three-dimensional structural homology with the major histocompatibility class 1/CD1 family of proteins, particularly CD1d. It binds activated protein C and enhances protein C activation by the thrombin-thrombomodulin complex. It plays a role in the protein C pathway controlling blood coagulation.
Protocols
| Product Specific Protocols | |
|---|---|
| FC protocol for PROCR/EPCR/CD201 antibody 98325-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
