Product Information
98325-1-PBS targets EPCR/CD201 in FC applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Recombinant protein Predict reactive species |
Full Name | protein C receptor, endothelial (EPCR) |
Calculated Molecular Weight | 238 aa, 27 kDa |
GenBank Accession Number | BC014451 |
Gene Symbol | PROCR |
Gene ID (NCBI) | 10544 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9UNN8 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
EPCR (endothelial cell protein C receptor), also known as CD201, is a type 1 transmembrane protein that is primarily found on endothelial cells. It exhibits sequence and three-dimensional structural homology with the major histocompatibility class 1/CD1 family of proteins, particularly CD1d. It binds activated protein C and enhances protein C activation by the thrombin-thrombomodulin complex. It plays a role in the protein C pathway controlling blood coagulation.