ERBB2IP Recombinant monoclonal antibody

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• ERBB2IP Recombinant monoclonal antibody (87639-1-RR)

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  WB analysis using 87639-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 87639-1-RR (ERBB2IP antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

ERBB2IP Uni-rAb^® Recombinant Antibody for WB, ELISA

Cat No. 87639-1-RR

Clone No.253133B5

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

LAP2, Densin 180 like protein, Densin-180-like protein, Erbb2-interacting protein, ERBIN

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Tested Applications

• Positive WB detected in: HeLa cells, HEK-293T cells, Jurkat cells, U2OS cells, MCF-7 cells, MDA-MB-231 cells

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:5000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

87639-1-RR targets ERBB2IP in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Eg5491

  Product name: Recombinant human ERBIN protein

  Source: mammalian cells-derived, V37

  Tag: C-rFc

  Domain: 950-1100 aa of NM_001253697.1

  Sequence: HNPEEPNIIRGPTSGPQSAPQIYGPPQYNIQYSSSAAVKDTLWHSKQNPQIDHASFPPQLLPRSESTENQSYAKHSANMNFSNHNNVRANTAYHLHQRLGPARHGEMWAISPNDRLIPAVTRSTIQRQSSVSSTASVNLGDPGSTRRAQIP

• Full Name: erbb2 interacting protein
• Calculated Molecular Weight: 158 kDa
• Observed Molecular Weight: 150-180 kDa
• GenBank Accession Number: NM_001253697.1
• Gene Symbol: ERBB2IP
• Gene ID (NCBI): 55914
• RRID: AB_3745668
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q96RT1-1
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ERBB2IP is a cytoplasmic protein that contains leucine-rich repeats (LRR) and PSD95/Dlg1/zo-1 (PDZ) domain (thus named a LAP protein). ERBB2IP interacts, via its single PDZ domain, specifically with ErbB2, but not with ErbB3, ErbB4, or EGFR. It is colocalized with ErbB2 at the basolateral membranes of epithelial cells. In addition, ERBB2IP also interacts with PSD‐95, Lano and with three p120‐related catenins, eBPAG1 and the β4 subunit of the α6β4 integrin, two major components of hemidesmosomes. The molecular weight of ERBB2IP was predicted 150~180 kDa by Western Blot.(PMID: 25288731,PMID: 24252174,PMID: 19289088)