ERK1/2 Antibody 5 Publications

Mouse Monoclonal| Catalog number: 66192-1-Ig |CloneNo.: 4G8A11

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Freight/Packing

Con: 186 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
HeLa cells, HepG2 cells, MCF-7 cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human ovary tumor tissue, human cervical cancer tissue, human ovary tumor tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:1000-1:4000 for WB
IHC : 1:100-1:400
IF : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
mitogen-activated protein kinase 3

Calculated molecular weight:
44 kDa

Observed molecular weight:
38 kDa,43 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MAPK3

Synonyms
ERK, ERK 1, ERK1, ERK1/2, ERT2, HS44KDAP, HUMKER1A, Insulin stimulated MAP2 kinase, MAP kinase 1, MAP kinase 3, MAP kinase isoform p44, MAPK 1, MAPK 3, MAPK3, p44 ERK1, p44 MAPK, P44ERK1, P44MAPK, PRKM3
Background

ERK1 and ERK2 belongs to the protein kinase superfamily. It is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. ERK1/2 catalized the reaction: ATP + a protein = ADP + a phosphoprotein. It is activated by tyrosine phosphorylation in response to insulin and NGF.


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