Product Information
85377-1-PBS targets ERLIN1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | ERLIN1 fusion protein Ag11393 Predict reactive species |
| Full Name | ER lipid raft associated 1 |
| Calculated Molecular Weight | 346 aa, 39 kDa |
| Observed Molecular Weight | 39 kDa |
| GenBank Accession Number | BC031791 |
| Gene Symbol | ERLIN1 |
| Gene ID (NCBI) | 10613 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | O75477 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
ERLIN1, also known as Erlin-1 or SPFH1, stands for "ER lipid raft-associated protein 1." It is a protein-coding gene that plays a significant role in cellular processes, particularly in the endoplasmic reticulum (ER). The ER is a crucial organelle involved in protein synthesis, lipid metabolism, and calcium homeostasis. ERLIN1 is part of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) domain-containing family of proteins, which are often associated with lipid rafts-microdomains within cellular membranes that are enriched in cholesterol and sphingolipids. ERLIN1 is involved in the regulation of protein degradation, particularly through the ER-associated degradation (ERAD) pathway (PMID: 37683630).
