Endoglin/CD105 Recombinant antibody

Endoglin/CD105 Recombinant Antibody for WB, ELISA
Cat No. 84807-5-RR
Clone No.242305A11

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, ELISA

CD105, 242305A11, S endoglin, Eng, endoglin

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive WB detected inbEnd.3 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

84807-5-RR targets Endoglin/CD105 in WB, ELISA applications and shows reactivity with mouse samples.

Tested Reactivity mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein Predict reactive species
Full Name endoglin
Calculated Molecular Weight70kDa
Observed Molecular Weight90 kDa
GenBank Accession NumberNM_007932.2
Gene Symbol CD105
Gene ID (NCBI) 13805
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ63961
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)

Protocols

Product Specific Protocols
WB protocol for Endoglin/CD105 antibody 84807-5-RRDownload protocol
Standard Protocols
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