|Positive IF detected in||human umbilical vein endothelial cells, HUVEC cells|
|Immunofluorescence (IF)||IF : N/A|
|Sample-dependent, check data in validation data gallery|
The immunogen of 21485-1-AP is F8 Fusion Protein expressed in E. coli.
|Host / Isotype||Rabbit / IgG|
|Immunogen||F8 fusion protein Ag15772|
|Full Name||coagulation factor VIII, procoagulant component|
|Calculated molecular weight||2351 aa, 267 kDa|
|GenBank accession number||BC022513|
|Gene ID (NCBI)||2157|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
F8, also named as AHF and F8C, belongs to the multicopper oxidase family. F8, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa. F8 can be cleaved to 4 chains: F8a heavy chain, 200 kDa isoform, F8a heavy chain, 92 kDa isoform, F8 B chain and F8a light chain. This antibody can recognize the light chain.