Product Information
32720-1-PBS targets FAM69C in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag37611 Product name: Recombinant human DIPK1C protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 300-419 aa of NM_001044369 Sequence: MAFFEPKMREILEQNCTGDEDCNFFDCFSRCDLRVNKCGAQRVNNNLQVICDKIFRHWFSAPLKSSAVSFQLQLQLQEAVQECADPGVPSGNTRRAASSVFWKLRQLLQATLRELQEAEK Predict reactive species |
| Full Name | chromosome 18 open reading frame 51 |
| Calculated Molecular Weight | 46 kDa |
| Observed Molecular Weight | 46 kDa, 55 kDa, 32 kDa |
| GenBank Accession Number | NM_001044369 |
| Gene Symbol | C18orf51 |
| Gene ID (NCBI) | 125704 |
| RRID | AB_3742722 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q0P6D2 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
FAM69C is a kinase critically involved in neurodegenerative dementia. Biochemical analyses uncover that FAM69C is a serine/threonine kinase. Phosphoproteomic characterizations reveal that FAM69C substrates are involved in synaptic structure and function. Reduced levels of FAM69C are found in postmortem brains of Alzheimer's disease patients. FAM69C is a protective regulator of memory and a potential therapeutic target for memory loss in neurodegenerative dementia (PMID: 35858575). FAM69C undergoes glycosylation modification, and a 55 kDa band was observed in the literature (PMID: 35858575). The mouse FAM69C has two isoforms, and the predicted molecular weight is 46 kDa and 30 kDa.
