FDPS Polyclonal antibody, PBS Only

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• FDPS Polyclonal antibody, PBS Only (16129-1-PBS)

• 

  WB analysis using 16129-1-AP (same clone as 16129-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 16129-1-AP (FDPS antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16129-1-PBS in a different storage buffer formulation.

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  WB analysis of A431 using 16129-1-AP (same clone as 16129-1-PBS)

  WB result of FDPS antibody (16129-1-AP; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-FDPS transfected A431 cells. This data was developed using the same antibody clone with 16129-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rat liver using 16129-1-AP (same clone as 16129-1-PBS)

  rat liver tissue were subjected to SDS PAGE followed by western blot with 16129-1-AP (FDPS antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16129-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human cerebellum using 16129-1-AP (same clone as 16129-1-PBS)

  human cerebellum tissue were subjected to SDS PAGE followed by western blot with 16129-1-AP (FDPS antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16129-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse liver using 16129-1-AP (same clone as 16129-1-PBS)

  IP result of anti-FDPS (IP:16129-1-AP, 4ug; Detection:16129-1-AP 1:1000) with mouse liver tissue lysate 4000ug. This data was developed using the same antibody clone with 16129-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

FDPS Polyclonal Antibody for WB, IP, Indirect ELISA

Cat No. 16129-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, Indirect ELISA

Synonyms

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Product Information

16129-1-PBS targets FDPS in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag9115

  Product name: Recombinant human FDPS protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 68-419 aa of BC010004

  Sequence: NGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK

• Full Name: farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
• Calculated Molecular Weight: 419 aa, 48 kDa
• Observed Molecular Weight: 39-41 kDa
• GenBank Accession Number: BC010004
• Gene Symbol: FDPS
• Gene ID (NCBI): 2224
• RRID: AB_2104749
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P14324
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

FPPS (also known as FDPS) is a key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. The expression of FPPS was elevated in prostate tumor cell lines, indicating its potential role in prostate cancer progression.