FceR1a Recombinant antibody, PBS Only

FceR1a {ptg:Brand} Recombinant Antibody for WB, Indirect ELISA
Cat No. 84662-3-PBS
Clone No.241848D1

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

FceRIa, FcERI, Fc-epsilon RI-alpha, FCE1A, Fc epsilon RI alpha

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

84662-3-PBS targets FceR1a in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein Predict reactive species
Full Name Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Calculated Molecular Weight30kDa
Observed Molecular Weight55-65 kDa
GenBank Accession NumberNM_001387280.1
Gene Symbol FceR1a
Gene ID (NCBI) 2205
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP12319
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

Fc epsilon Receptor I alpha (FceR1a) is a single-pass type I membrane protein that contains 2 immunoglobulin-like domains. FceR1a forms a tetrameric complex, FceRI, with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316). The calculated molecular weight of FceR1a is 30 kDa, the 55- to 70-kDa bands detected by this antibody are probably caused by heterogeneous glycosylation (PMID: 11344350; 12671054).

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