Anti-Human Frizzled 2 Rabbit Recombinant Antibody, PBS Only

• 

  SEC-HPLC of 98707-1-RR

  The purity of Human Frizzled 2 Recombinant monoclonal antibody (Cat. No. 98707-1-RR) was greater than 95% as determined by SEC-HPLC.

• 

  FC experiment of THP-1 using 98707-1-RR (same clone as 98707-1-PBS)

  1x10^6 THP-1 cells were surface stained with 0.25 ug Anti-Human Frizzled 2 Rabbit RecAb (98707-1-RR, Clone: 251644E1) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98707-1-PBS in a different storage buffer formulation.

Frizzled 2 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98707-1-PBS

Clone No.251644E1

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

FZD2, Frizzled-2, Fz 2, Fz-2, FzE2

---

Product Information

98707-1-PBS targets Frizzled 2 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: frizzled homolog 2 (Drosophila)
• Calculated Molecular Weight: 565 aa, 64 kDa
• GenBank Accession Number: BC113402
• Gene Symbol: Frizzled 2
• Gene ID (NCBI): 2535
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q14332
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Frizzled 2(FZD2) also known as FzE2, which belongs to the G-protein coupled receptor Fz/Smo family. FZD2 is an important receptor in the Wnt pathway, which is highly expressed in malignant tumors and helps regulate multiple tumor behaviors. Its expression level is related to prognosis. Moreover, high level of FZD2 had significant correlation with poor prognosis in Breast cancer (BC) patients(PMID: 33832493).