Anti-Human Frizzled 2 Rabbit Recombinant Antibody

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  SEC-HPLC of 98707-1-RR

  The purity of Human Frizzled 2 Recombinant monoclonal antibody (Cat. No. 98707-1-RR) was greater than 95% as determined by SEC-HPLC.

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  FC experiment of THP-1 using 98707-1-RR

  1x10^6 THP-1 cells were surface stained with 0.25 ug Anti-Human Frizzled 2 Rabbit RecAb (98707-1-RR, Clone: 251644E1) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

Frizzled 2 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98707-1-RR

Clone No.251644E1

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

FZD2, Frizzled-2, Fz 2, Fz-2, FzE2

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Tested Applications

• Positive FC detected in: THP-1 cells

Recommended dilution

• Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension

This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

98707-1-RR targets Frizzled 2 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: frizzled homolog 2 (Drosophila)
• Calculated Molecular Weight: 565 aa, 64 kDa
• GenBank Accession Number: BC113402
• Gene Symbol: Frizzled 2
• Gene ID (NCBI): 2535
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q14332
• Storage Buffer: PBS with 0.09% sodium azide, pH 7.3.
• Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.

Background Information

Frizzled 2(FZD2) also known as FzE2, which belongs to the G-protein coupled receptor Fz/Smo family. FZD2 is an important receptor in the Wnt pathway, which is highly expressed in malignant tumors and helps regulate multiple tumor behaviors. Its expression level is related to prognosis. Moreover, high level of FZD2 had significant correlation with poor prognosis in Breast cancer (BC) patients(PMID: 33832493).