G3BP1 Recombinant antibody
G3BP1 Recombinant Antibody for IF, ELISA
Host / Isotype
Rabbit / IgG
Cat no : 80777-1-RR
|Positive IF detected in
|sodium arsenite treated HeLa cells
|IF : 1:500-1:2000
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
80777-1-RR targets G3BP1 in IF, ELISA applications and shows reactivity with Human samples.
|Host / Isotype
|Rabbit / IgG
|G3BP1 fusion protein Ag3728
|GTPase activating protein (SH3 domain) binding protein 1
|Calculated molecular weight
|466 aa, 52 kDa
|GenBank accession number
|Gene ID (NCBI)
|Protein A purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
GAP SH3 Binding Protein 1 (G3BP1), also named as G3BP, is an effector of stress granule (SG) assembly. SG biology plays an important role in the pathophysiology of TDP-43 in ALS and FTLD-U. G3BP1 can be used as a marker of SG. It has been shown to function downstream of Ras and play a role in RNA metabolism, signal transduction, and proliferation. G3BP1 is a ubiquitously expressed protein that localizes to the cytoplasm in proliferating cells and to the nucleus in non-proliferating cells. G3BP1 has recently been implicated in cancer biology.