GGTLC2 Polyclonal antibody

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  WB analysis using 18191-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 18191-1-AP (GGTLC2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 18191-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 18191-1-AP (GGTLC2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

GGTLC2 Polyclonal Antibody for WB, ELISA

Cat No. 18191-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Synonyms

Gamma-glutamyltransferase light chain 2, Gamma-glutamyltransferase-like protein 4, GGTL4, Glutathione hydrolase light chain 2

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Tested Applications

• Positive WB detected in: 786-O cells, human urine sample, human milk, mouse kidney tissue

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

18191-1-AP targets GGTLC2 in WB, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: GGTLC2 fusion protein Ag12911
• Full Name: gamma-glutamyltransferase light chain 2
• Calculated Molecular Weight: 218 aa, 24 kDa
• Observed Molecular Weight: 24 kDa
• GenBank Accession Number: BC069534
• Gene Symbol: GGTLC2
• Gene ID (NCBI): 91227
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q14390
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

GGT is a protease anchored to the cell membrane, consisting of a light chain and a heavy chain. GGTLC2 (Glutathione hydrolase light chain 2), also known as GGTL4, a constituent of the GGT family, has been characterized as an antioxidant gene, with emerging evidence indicating a potential link between its expression levels and sarcoma patient outcome (PMID: 40191433). Studies have shown that GGTLC2 is highly expressed in gastric cancer, promoting cell proliferation, invasion, and migration while inhibiting apoptosis and ferroptosis.