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  • KD/KO Validated

GIPC1 Polyclonal antibody

GIPC1 Polyclonal Antibody for WB, IP, IF, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 14822-1-AP


C19orf3, GIPC, GIPC1, GLUT1CBP, Hs.6454, IIP 1, NIP, RGS GAIP interacting protein, RGS19 interacting protein 1, RGS19IP1, SEMCAP, SYNECTIIN, SYNECTIN, Tax interaction protein 2, TIP 2

Tested Applications

Positive WB detected inHepG2 cells, mouse skeletal muscle tissue, mouse brain tissue, rat brain tissue
Positive IP detected inmouse brain tissue
Positive IHC detected inhuman breast cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHepG2 cells, A2780 cells

Recommended dilution

Western Blot (WB)WB : 1:600-1:4000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:10-1:100
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

14822-1-AP targets GIPC1 in WB, IP, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen GIPC1 fusion protein Ag6597
Full Name GIPC PDZ domain containing family, member 1
Calculated Molecular Weight 36 kDa
Observed Molecular Weight 42 kDa
GenBank Accession NumberBC000410
Gene Symbol GIPC1
Gene ID (NCBI) 10755
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

GAIP interacting protein C terminus, member 1(GIPC1), also known as PDZ domain-containing protein GIPC1, is a cytoplasmic protein that also localizes to the peripheral membrane, acting as an adaptor protein linking receptor interactions to intracellular signaling pathways, including cell cycle regulation, and expression has been associated with some cancers (PMID: 19175293, 26757732). This antibody is specific to GIPC1 with a band at 42 kDa (PMID: 18721486).


Product Specific Protocols
WB protocol for GIPC1 antibody 14822-1-APDownload protocol
IHC protocol for GIPC1 antibody 14822-1-APDownload protocol
IF protocol for GIPC1 antibody 14822-1-APDownload protocol
IP protocol for GIPC1 antibody 14822-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Am J Hum Genet

Expansion of GGC Repeat in GIPC1 Is Associated with Oculopharyngodistal Myopathy.

Authors - Jianwen Deng

Dev Cell

SH3BP4 promotes neuropilin-1 and α5-integrin endocytosis and is inhibited by Akt.

Authors - Christoph J Burckhardt

Ann Neurol

GIPC1 CGG repeat expansion is associated with movement disorders.

Authors - Yu Fan


G protein-coupled receptor GPR151 is involved in trigeminal neuropathic pain through the induction of Gβγ/extracellular signal-regulated kinase-mediated neuroinflammation in the trigeminal ganglion.

Authors - Bao-Chun Jiang


BMP9 directly induces rapid GSK3-β phosphorylation in a Wnt-independent manner through class I PI3K-Akt axis in osteoblasts.

Authors - Nahoko Eiraku
  • KD Validated

CNS Neurosci Ther

G-alpha interacting protein interacting protein, C terminus 1 regulates epileptogenesis by increasing the expression of metabotropic glutamate receptor 7.

Authors - Yong Liu


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Tom (Verified Customer) (11-02-2023)

Used at 1:2000 on PVDF membrane, overnight incubation at 4C in 3% BSA PBS 0.1% Tween. No non-specific bands and band reduced by knockdown with GIPC1 siRNA. Diluted antibody succesfully re0used after freezing at -20C

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:2000
  • Cell Tissue Type: HUVEC
GIPC1 Antibody Western Blot validation (1:2000 dilution) in HUVEC (Cat no:14822-1-AP)

Sophy (Verified Customer) (01-27-2023)

I ordered a GIPC1 antibody from another company before and the results were poor. Proteintech antibody worked very well with the dilution of 1:1000 in western.

  • Applications: Western Blot
  • Cell Tissue Type: NSCLC cells