GLIPR2 Polyclonal antibody, PBS Only

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• GLIPR2 Polyclonal antibody, PBS Only (16508-1-PBS)

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  WB analysis of human milk using 16508-1-AP (same clone as 16508-1-PBS)

  human milk were subjected to SDS PAGE followed by western blot with 16508-1-AP (GLIPR2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16508-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung using 16508-1-AP (same clone as 16508-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung tissue slide using 16508-1-AP (GLIPR2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16508-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung using 16508-1-AP (same clone as 16508-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung tissue slide using 16508-1-AP (GLIPR2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16508-1-PBS in a different storage buffer formulation.

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  IF Staining of A431 using 16508-1-AP (same clone as 16508-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed A431 cells using GLIPR2 antibody (16508-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 16508-1-PBS in a different storage buffer formulation.

GLIPR2 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Cat No. 16508-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IF/ICC, Indirect ELISA

Synonyms

Glioma pathogenesis-related protein 2, GLI pathogenesis related 2, GAPR-1, GAPR1, GAPR 1

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Product Information

16508-1-PBS targets GLIPR2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag9725

  Product name: Recombinant human GLIPR2 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-90 aa of BC017918

  Sequence: MGKSASKQFHNEVLKAHNEYRQKHGVPPLKLCKNLNREAQQYSEALASTRILKHSPESSRGQCGENLAWASYDQTGKEVADRWYSEVHFM

• Full Name: GLI pathogenesis-related 2
• Calculated Molecular Weight: 153aa,17 kDa; 90aa,10 kDa
• Observed Molecular Weight: 17 kDa
• GenBank Accession Number: BC017918
• Gene Symbol: GLIPR2
• Gene ID (NCBI): 152007
• RRID: AB_3669246
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9H4G4
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Golgi-associated plant pathogenesis-related protein 1 (GLIPR2, also known as C9orf19 and GAPR1) is a multifunctional protein with dual engagement in normal cellular processes and the intricacies of cancer biology. GLIPR2 has also been associated with a spectrum of cellular functions encompassing the regulation of autophagy (PMID: 12137952; 18824526). It has been reported that GLIPR2 is a newly identified negative regulator of autophagy that inhibits the class III phosphatidylinositol 3-kinase complex I (PtdIns3K-C1) complex activity (PMID: 33222586).