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GLRX2 Polyclonal antibody

GLRX2 Polyclonal Antibody for WB, IF, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 13381-1-AP


GLRX2, Glutaredoxin 2, Glutaredoxin 2, mitochondrial, GRX2

Tested Applications

Positive WB detected inHGC-27 cells, MCF-7 cells
Positive IF detected inMCF-7 cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:2000
Immunofluorescence (IF)IF : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

13381-1-AP targets GLRX2 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen GLRX2 fusion protein Ag4218
Full Name glutaredoxin 2
Calculated Molecular Weight 164 aa, 18 kDa
Observed Molecular Weight 16 kDa
GenBank Accession NumberBC028113
Gene Symbol GLRX2
Gene ID (NCBI) 51022
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

GLRX2(Glutaredoxin-2) is also named as GRX2 and belongs to the glutaredoxin family. It facilitates the maintenance of cellular redox homeostasis upon treatment with apoptotic agents, thereby preventing cardiolipin oxidation and cytochrome C release. The GLRX2, which exists in a dynamic equilibrium of enzymatically active monomers and quiescent dimers,is a 16-kDa protein directed either to the nucleus or to the mitochondria through differential splicing of the first exon(PMID: 17121859). It has 2 isoforms produced by alternative splicing.


Product Specific Protocols
WB protocol for GLRX2 antibody 13381-1-APDownload protocol
IF protocol for GLRX2 antibody 13381-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols




Hepatic AMPK signaling dynamic activation in response to REDOX balance are sentinel biomarkers of exercise and antioxidant intervention to improve blood glucose control

Authors - Meiling Wu

Free Radic Biol Med

Compartmentally scavenging hepatic oxidants through AMPK/SIRT3-PGC1α axis improves mitochondrial biogenesis and glucose catabolism.

Authors - Meiling Wu

Free Radic Biol Med

Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.

Authors - Kelei Dong
  • KD Validated

Int Immunopharmacol

Glutaredoxin 2 protects cardiomyocytes from hypoxia/reoxygenation-induced injury by suppressing apoptosis, oxidative stress, and inflammation via enhancing Nrf2 signaling.

Authors - Chengliang Li

Brain Res

Upregulation of Glutaredoxin 2 alleviates oxygen-glucose deprivation/reoxygenation-induced apoptosis and ROS production in neurons by enhancing Nrf2 signaling via modulation of GSK-3β.

Authors - Jian Wen
  • KD Validated

J Physiol Sci

Redox proteins are constitutively secreted by skeletal muscle.

Authors - Yasuko Manabe