- Featured Product
- KD/KO Validated
CoraLite® Plus 488-conjugated GSK3B Polyclonal antibody
GSK3B Polyclonal Antibody for IF
Host / Isotype
Rabbit / IgG
human, mouse, rat
CoraLite® Plus 488 Fluorescent Dye
Cat no : CL488-22104
|Positive IF detected in
|IF : 1:50-1:500
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
CL488-22104 targets GSK3B in IF applications and shows reactivity with human, mouse, rat samples.
|human, mouse, rat
|Host / Isotype
|Rabbit / IgG
|GSK3B fusion protein Ag17320
|glycogen synthase kinase 3 beta
|Calculated molecular weight
|433 aa, 48 kDa
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|CoraLite® Plus 488 Fluorescent Dye
|Excitation/Emission maxima wavelengths
|493 nm / 522 nm
|Antigen affinity purification
|PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
|Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase.GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to INS regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Researches showed that the crystal structure of human GSK3B, expressed in insect cells, at 2.8-angstrom resolution. This antibody recognize the C-terminal of GSK3B.