HRAS-Specific Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 18295-1-AP

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Freight/Packing

Con: 46 μg/150 μl

Choose size:

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Species specificity:
human, mouse

Positive WB detected in:
HEK-293 cells, PC-3 cells, NIH/3T3 cells

Positive IP detected in:
HEK-293 cells

Positive IHC detected in:
human kidney tissue, human prostate hyperplasia tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:200-1:1000
IP : 0.5-4.0 ug for IP and 1:1000-1:6000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
v-Ha-ras Harvey rat sarcoma viral oncogene homolog

Calculated molecular weight:
21 kDa

Observed molecular weight:
21 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
HRAS

Synonyms
C BAS/HAS, C H RAS, C HA RAS1, CTLO, GTPase HRas, H Ras 1, H RASIDX, Ha Ras, HAMSV, HRAS, HRAS1, K RAS, p21ras, RASH1, Transforming protein p21
Background

HRAS,also named as c-bas/has and RASH1, is v-Ha-ras Harvey rat sarcoma viral oncogene homolog from the mammalian ras gene family and it is a member of the small GTPase superfamily. RAS proteins are involved in signal transduction pathways, and bind GDP/GTP and possess intrinsic GTPase activity. Defects in HRAS are a cause of cancer. The antibody is specific to HRAS, can’t recognize NRAS and KRAS.


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