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  • KD/KO Validated

HRAS-Specific Polyclonal antibody

HRAS-Specific Polyclonal Antibody for FC (Intra), IF, IP, WB, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat


WB, IP, IHC, IF, FC (Intra), ELISA



Cat no : 18295-1-AP


C BAS/HAS, C H RAS, C HA RAS1, CTLO, GTPase HRas, H Ras 1, H RASIDX, Ha Ras, HAMSV, HRAS, HRAS1, HRAS-Specific, K RAS, RASH1, Transforming protein p21

Tested Applications

Positive WB detected inHEK-293 cells, PC-3 cells, SH-SY5Y cells, C6 cells, NIH/3T3 cells, mouse kidney tissue, rat tissue
Positive IP detected inmouse brain tissue, HEK-293 cells
Positive IF detected inMCF-7 cells
Positive FC detected inHeLa cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
Immunofluorescence (IF)IF : 1:200-1:800
Sample-dependent, check data in validation data gallery

Product Information

18295-1-AP targets HRAS-Specific in WB, IP, IHC, IF, FC (Intra), ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name v-Ha-ras Harvey rat sarcoma viral oncogene homolog
Calculated molecular weight 21 kDa
Observed molecular weight 21 kDa
GenBank accession numberBC006499
Gene symbol HRAS
Gene ID (NCBI) 3265
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

HRAS, also named as c-bas/has and RASH1, is v-Ha-ras Harvey rat sarcoma viral oncogene homolog from the mammalian ras gene family and it is a member of the small GTPase superfamily. RAS proteins are involved in signal transduction pathways, and bind GDP/GTP and possess intrinsic GTPase activity. Defects in HRAS are a cause of cancer. The antibody is specific to HRAS, can't recognize NRAS and KRAS.


Product Specific Protocols
WB protocol for HRAS-Specific antibody 18295-1-APDownload protocol
IF protocol for HRAS-Specific antibody 18295-1-APDownload protocol
IP protocol for HRAS-Specific antibody 18295-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Sci Transl Med

Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRAS.

Authors - Sarah J Ross

Sci Transl Med

The ERBB network facilitates KRAS-driven lung tumorigenesis.

Authors - Björn Kruspig

Mol Cell

KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis

Authors - Hiroshi Senoo

J Exp Med

Genome-wide CRISPR/Cas9 screens reveal shared and cell-specific mechanisms of resistance to SHP2 inhibition

Authors - Wei Wei

Nat Commun

KRAS regulation by small non-coding RNAs and SNARE proteins.

Authors - Yonglu Che

Nat Commun

A potent KRAS macromolecule degrader specifically targeting tumours with mutant KRAS.

Authors - Nicolas Bery


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Benjamin (Verified Customer) (01-10-2020)

Identified HRAS around 20kDa mark on western blot.

  • Applications: Western Blot,
  • Primary Antibody Dilution: 1:1000
  • Cell Tissue Type: HEK