Recombinant Human IFNA8 protein (rFc Tag)

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• Recombinant Human IFNA8 protein (rFc Tag) (Eg4954)

Species

Human

Purity

>90 %, SDS-PAGE

Tag

rFc Tag

Activity

not tested

Cat no : Eg4954

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Validation Data Gallery

• 

  Purity of Recombinant Human IFNA8 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

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Product Information

• Purity: >90 %, SDS-PAGE
• Endotoxin: <0.1 EU/μg protein, LAL method
• Activity:

  Not tested

• Expression: HEK293-derived Human IFNA8 protein Cys24-Glu189 (Accession# P32881) with a rabbit IgG Fc tag at the N-terminus.
• GeneID: 3445
• Accession: P32881
• PredictedSize: 46.7 kDa
• SDS-PAGE: 45-50 kDa, reducing (R) conditions
• Formulation: Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
• Reconstitution: Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
• Storage Conditions:
  It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
• Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. IFNA4 is predicted to enable cytokine activity and type I interferon receptor binding activity, and might be involved in several processes, including B cell activation.

References:

1. Pestka S. et al. (1987). Annu. Rev. Biochem. 56:727.
2. Mattei F. et al. (2010). Cytokine Growth Factor Rev. 21(4):227-36.