Recombinant Human IFNAR2 protein (rFc Tag) (HPLC verified)
Species
Human
Purity
>90 %, SDS-PAGE
>90 %, SEC-HPLC
Tag
rFc Tag
Activity
not tested
Cat no : Eg2928
Validation Data Gallery
Product Information
Purity | >90 %, SDS-PAGE >90 %, SEC-HPLC |
Endotoxin | <0.1 EU/μg protein, LAL method |
Activity |
Not tested |
Expression | HEK293-derived Human IFNAR2 protein Ile27-Lys243 (Accession# P48551-1) with a rabbit IgG Fc tag at the C-terminus. |
GeneID | 3455 |
Accession | P48551-1 |
PredictedSize | 50.8 kDa |
SDS-PAGE | 55-80 kDa, reducing (R) conditions |
Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
IFNAR2 is a type I membrane protein and is part of one of the two chains of a receptor for interferon (IFN), alpha and beta. IFNAR2 has three isoforms, the first of which is a non-functional protein with a truncated cytoplasmic domain. The second is lengthy and includes the functional trans-membrane protein together with IFNAR1. The soluble version of the receptor is the third form (sIFNAR2).
References:
1. Órpez-Zafra T. et al. (2017). Mult. Scler. J. 23:937–945. 2. López-Bielma MF. et al. (2023) Pathogens. 12(11):1320.