Recombinant Human PTPRZ1 protein (rFc Tag)

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• Recombinant Human PTPRZ1 protein (rFc Tag) (Eg5898)

Species

Human

Purity

>90 %, SDS-PAGE

Tag

rFc Tag

Activity

not tested

Cat no : Eg5898

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Validation Data Gallery

• 

  Purity of Recombinant Human PTPRZ1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

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Product Information

• Purity: >90 %, SDS-PAGE
• Endotoxin: <0.1 EU/μg protein, LAL method
• Activity:

  Not tested

• Expression: HEK293-derived Human PTPRZ1 protein Arg30-Glu420 (Accession# P23471-1) with a rabbit IgG Fc tag at the C-terminus.
• GeneID: 5803
• Accession: P23471-1
• PredictedSize: 70.1 kDa
• SDS-PAGE: 70-95 kDa, reducing (R) conditions
• Formulation: Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
• Reconstitution: Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
• Storage Conditions:
  It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
• Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

PTPRZ1, also named as HTPZP2, PTPRZ, PTPRZ2, and PTPZ, belongs to the protein-tyrosine phosphatase family and Receptor class 5 subfamily. It regulates cell signal transduction by catalyzing tyrosine dephosphorylation, playing a key role in neural stem cell proliferation, glial cell development, and axonal guidance.

References:

1.Nagai, Kenichiro et al.International journal of molecular sciences vol. 23,8 4414. 16 Apr. 2022
2.Xia, Zhenkun et al. Journal of Cancer vol. 10,7 1663-1674. 2 Apr. 2019,