Recombinant Human TSPAN7 protein (rFc Tag)(HPLC verified)

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• Recombinant Human TSPAN7 protein (rFc Tag)(HPLC verified) (Eg2323)

Species

Human

Purity

>90 %, SDS-PAGE
>90 %, SEC-HPLC

Tag

C-rFc

Activity

not tested

Cat no : Eg2323

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Validation Data Gallery

• 

  Purity of Recombinant Human TSPAN7 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

• 

  The purity of Human TSPAN7 was greater than 90% as determined by SEC-HPLC.

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Product Information

• Purity: >90 %, SDS-PAGE; >90 %, SEC-HPLC
• Endotoxin: <0.1 EU/μg protein, LAL method
• Activity:

  Not tested

• Expression: HEK293-derived Human TSPAN7 protein Arg113-Met213 (Accession# AAH18036.1) with a rabbit IgG Fc tag at the C-terminus.
• GeneID: 7102
• Accession: AAH18036.1
• PredictedSize: 37.9 kDa
• SDS-PAGE: 42-55 kDa, reducing (R) condition
• Formulation: Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
• Reconstitution: Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
• Storage Conditions:
  It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
• Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

TSPAN7, also named as A15, MXS1, CD231, MRX58, CCG-B7, TM4SF2, TALLA-1, TM4SF2b and DXS1692E, is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TSPAN7 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. TSPAN7 may be involved in cell proliferation and cell motility. It is not solely expressed in T cells, but also expressed in acute myelocytic leukemia cells of some patients (PMID: 39175035; 38649381).

References:

1. Lu B. et al. (2024). Biol Direct. 19(1):72.
2. Zhang H. et al. (2024). Cell Death Discov. 10(1):187.