IDO1 Monoclonal antibody, PBS Only
IDO1 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, rat
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3G2G11
Cat no : 66528-1-PBS
Synonyms
Validation Data Gallery
Product Information
66528-1-PBS targets IDO1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Reactivity | Human, mouse, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | IDO1 fusion protein Ag3953 |
Full Name | indoleamine 2,3-dioxygenase 1 |
Calculated Molecular Weight | 403 aa, 45 kDa |
Observed Molecular Weight | 42 kDa |
GenBank Accession Number | BC027882 |
Gene Symbol | IDO1 |
Gene ID (NCBI) | 3620 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
IDO1 is the target for therapy in a range of clinical settings, including cancer, chronic infections, autoimmune and allergic syndromes, and transplantation. Elevated IDO1 expression is a hallmark of major viral infections including HIV, HBV, HCV or influenza and also of major bacteria infections, such as Tb, CAP, listeriosis and sepsis. Pathogens are able to highjack the immunosuppressive effects of IDO1 and make use of them to facilitate their own life cycle. MW of IDO1 is 40-42kd (PMID: 14502282; 17055065).