NeutraKine™ IFN Gamma Monoclonal antibody
NeutraKine™ IFN Gamma Monoclonal Antibody for Neutralization,ELISA
Host / Isotype
Mouse / IgG1
Cat no : 69007-1-Ig
|Neutralization||Measured by its ability to neutralize Human IFN-gamma inhibition of HT-29 cell line (human colorectal adenocarcinoma cell line). The ND50 is typically 100-400 ng/mL in the presence of 5 ng/mL Human IFN-gamma.|
69007-1-Ig targets NeutraKine™ IFN Gamma in Neutralization,ELISA applications and shows reactivity with Human samples.
|Host / Isotype||Mouse / IgG1|
|Immunogen||human Humankine IFN Gamma protein HZ-1301|
|Full Name||IFN gamma|
|Gene ID (NCBI)||3458|
|Purification Method||Protein G purification|
|Storage Buffer||Sterile PBS.|
|Reconstitution||This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.|
|Stability and Storage||Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.|
Interferon gamma (IFNG) is a soluble cytokine that is the only member of the type II class of interferons. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. It has been identified in many studies as a biomarker for pleural tuberculosis (TB). Mutations in this gene are associated with aplastic anemia.
This antibody is used to Block/Neutralize Interferon gamma protein.