NeutraKine™ IFN gamma Antibody

NeutraKine™ IFN gamma Monoclonal Antibody for Neutralization, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

Neutralization, ELISA

Conjugate

Unconjugated

CloneNo.

1E10G7

Cat no : 69007-1-Ig

Synonyms

IFG, IFI, IFN gamma, IFNG, Immune interferon, Interferon gamma, interferon, gamma



Tested Applications

NeutralizationMeasured by its ability to neutralize Human IFN-gamma inhibition of HT-29 cell line (human colorectal adenocarcinoma cell line). The ND50 is typically 100-400 ng/mL in the presence of 5 ng/mL Human IFN-gamma.

Product Information

69007-1-Ig targets NeutraKine™ IFN gamma in Neutralization, ELISA applications and shows reactivity with Human samples.

<0.1 EU/μg
Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen human Humankine IFN gamma protein HZ-1301
Full Name IFN gamma
Calculated molecular weight
Observed molecular weight
GenBank accession number
Gene symbol IFNG
Gene ID (NCBI) 3458
Conjugate Unconjugated
Form Liquid
Purification Method Protein G purification
Storage Buffer Sterile PBS.
ReconsitutionThis product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
Stability and StorageLyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

Background Information

Interferon gamma (IFNG) is a soluble cytokine that is the only member of the type II class of interferons. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. It has been identified in many studies as a biomarker for pleural tuberculosis (TB). Mutations in this gene are associated with aplastic anemia.

This antibody is used to Block/Neutralize Interferon gamma protein.

Protocols

Product Specific Protocols
Neutralization protocol of NeutraKine™ IFN gamma antibody 69007-1-IgDownload protocol
Standard Protocols
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