Anti-Human IFNGR1/CD119 Rabbit Recombinant Antibody, PBS Only

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  FC experiment of human peripheral blood leukocytes using 98343-1-RR (same clone as 98343-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human IFNGR1/CD119 Rabbit RecAb (98343-1-RR, Clone: 242632A8) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98343-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human peripheral blood leukocytes using 98343-1-RR (same clone as 98343-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human IFNGR1/CD119 Rabbit RecAb (98343-1-RR, Clone: 242632A8) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98343-1-PBS in a different storage buffer formulation.

IFNGR1/CD119 Uni-rAb^TM Recombinant Antibody for FC

Cat No. 98343-1-PBS

Clone No.242632A8

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

IFNGR1, IFN-gamma receptor 1, IFN-gamma R1, IFN gamma receptor 1, IFN gamma R1

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Product Information

98343-1-PBS targets IFNGR1/CD119 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: interferon gamma receptor 1
• Calculated Molecular Weight: 54 kDa
• GenBank Accession Number: NM_000416.3
• Gene Symbol: IFNGR1
• Gene ID (NCBI): 3459
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P15260-1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Interferon-gamam (IFN-γ) is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Cellular responses to IFN-γ are activated through its interaction with a heterodimeric receptor consisting of two subunits, IFNGR1 (CD119) and IFNGR2. IFNGR1 is the ligand-binding subunit which binds IFN-γ with high affinity, whereas IFNGR2 serves as the accessory subunit. Two subunits bind one IFN-γ dimer. Defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. (PMID: 17981204; 946248; 10888113)