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  • Flow cytometry (FC) experiment of human peripheral blood leukocytes using Anti-Human IFNGR1/CD119 Rabbit Recombinant Antibod (98343-1-RR)

    FC experiment of human peripheral blood leukocytes using 98343-1-RR

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human IFNGR1/CD119 Rabbit RecAb (98343-1-RR, Clone: 242632A8) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

  • Flow cytometry (FC) experiment of human peripheral blood leukocytes using Anti-Human IFNGR1/CD119 Rabbit Recombinant Antibod (98343-1-RR)

    FC experiment of human peripheral blood leukocytes using 98343-1-RR

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human IFNGR1/CD119 Rabbit RecAb (98343-1-RR, Clone: 242632A8) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

Anti-Human IFNGR1/CD119 Rabbit Recombinant Antibody

IFNGR1/CD119 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98343-1-RR
Clone No.242632A8

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

IFNGR1, IFN-gamma receptor 1, IFN-gamma R1, IFN gamma receptor 1, IFN gamma R1

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

- +

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Tested Applications

Positive FC detected inhuman peripheral blood leukocytes

Recommended dilution

ApplicationDilution
Flow Cytometry (FC)FC : 0.25 ug per 10^6 cells in 100 μl suspension
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

98343-1-RR targets IFNGR1/CD119 in FC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein Predict reactive species
Full Name interferon gamma receptor 1
Calculated Molecular Weight54 kDa
GenBank Accession NumberNM_000416.3
Gene Symbol IFNGR1
Gene ID (NCBI) 3459
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP15260-1
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

Background Information

Interferon-gamam (IFN-γ) is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Cellular responses to IFN-γ are activated through its interaction with a heterodimeric receptor consisting of two subunits, IFNGR1 (CD119) and IFNGR2. IFNGR1 is the ligand-binding subunit which binds IFN-γ with high affinity, whereas IFNGR2 serves as the accessory subunit. Two subunits bind one IFN-γ dimer. Defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. (PMID: 17981204; 946248; 10888113)

Protocols

Product Specific Protocols
FC protocol for IFNGR1/CD119 antibody 98343-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols