FcZero-rAb® PE Anti-Mouse IL-1R2 Rabbit Recombinant Antibody

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• FcZero-rAb® PE Anti-Mouse IL-1R2 Rabbit Recombinant Antibody (PE-FcA98347)

• Zero Fc receptor binding
• Site-specific conjugation
• One universal isotype

IL-1R2 FcZero-rAb^® Recombinant Antibody for FC

Cat No. PE-FcA98347 Copied!

Clone No. 242602C1

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Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Synonyms

CD121 antigen-like family member B, CD121b, IL-1 type II receptor, Il1r2, IL-1R-2

• 

  FC experiment of mouse bone marrow cells using PE-FcA98347

  1x10^6 mouse bone marrow cells were surface stained with 0.1 ug PE Anti-Mouse IL-1R2 Rabbit RecAb (PE-FcA98347, Clone: 242602C1) or 0.1 ug PE Rabbit IgG Isotype Control RecAb (PE-FcA98136, Clone: 240953C9). Cells were not fixed.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive FC detected in: mouse bone marrow cells

Recommended dilution

• Flow Cytometry (FC): FC : 0.1 ug per 10^6 cells in a 100 µl suspension

This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

PE-FcA98347 targets IL-1R2 in FC applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Eg2956

  Product name: Recombinant Mouse IL-1R2 protein (rFc Tag) (HPLC verified)

  Source: mammalian cells-derived, V37

  Tag: C-rFc

  Domain: 14-355 aa of NM_010555.4

  Sequence: FTTPTVVHTGKVSESPITSEKPTVHGDNCQFRGREFKSELRLEGEPVVLRCPLAPHSDISSSSHSFLTWSKLDSSQLIPRDEPRMWVKGNILWILPAVQQDSGTYICTFRNASHCEQMSVELKVFKNTEASLPHVSYLQISALSTTGLLVCPDLKEFISSNADGKIQWYKGAILLDKGNKEFLSAGDPTRLLISNTSMDDAGYYRCVMTFTYNGQEYNITRNIELRVKGTTTEPIPVIISPLETIPASLGSRLIVPCKVFLGTGTSSNTIVWWLANSTFISAAYPRGRVTEGLHHQYSENDENYVEVSLIFDPVTREDLHTDFKCVASNPRSSQSLHTTVKE

• Full Name: interleukin 1 receptor, type II
• Calculated Molecular Weight: 46 kDa
• GenBank Accession Number: NM_010555.4
• Gene Symbol: Il1r2
• Gene ID (NCBI): 16178
• RRID: AB_3749882
• Conjugate: PE Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 496 nm, 565 nm / 578 nm
• Excitation Laser: Blue Laser (488 nm), Green Laser (532 nm), Yellow-Green Laser (561 nm)
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P27931
• Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.
• Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 serves as a negative regulator of IL-1 signaling, thereby suppressing inflammatory response.