Anti-Human IL-3RB/CD131 Rabbit Recombinant Antibody, PBS Only

IL-3RB/CD131 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98336-2-PBS
Clone No.241823B12

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

CSF2RB, CD131, CDw131, GM-CSF/IL-3/IL-5 receptor common beta subunit, IL3RB

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

98336-2-PBS targets IL-3RB/CD131 in FC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen IL-3RB/CD131 fusion protein Eg1662 Predict reactive species
Full Name colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Calculated Molecular Weight97kDa
GenBank Accession NumberNM_000395.3
Gene Symbol CSF2RB
Gene ID (NCBI) 1439
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP32927-1
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

IL-3RB/CD131, also known as CSF2RB, is the common subunit of the type I cytokine receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3 and IL-5. CD131 is expressed on various immune cells, including hematopoietic progenitor cells, granulocytes, monocytes, macrophages, eosinophils, and mast cells, which plays a crucial role in mediating the effects of cytokines (PMID: 18412971). Tregs of healthy donors constitutively transcribe CSF2RB, but protein expression was much higher after TCR stimulation (PMID: 36532080, 3557440).

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