IL12A Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60324-1-Ig |CloneNo.: 6A10A8

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Con: 164 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Recombinant protein

Positive IHC detected in:
human kidney tissue, human kidney tissue, human tonsillitis tissue

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

Calculated molecular weight:
25 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IL12A

Synonyms
CLMF, CLMF p35, IL 12 subunit p35, IL 12A, IL12A, Interleukin 12 subunit alpha, NFSK, NKSF1, P35
Background

IL12A is a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.


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