IL-17RE Polyclonal antibody

IL-17RE Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IF, IHC, ELISA

Conjugate

Unconjugated

Publications

2

Cat no : 11984-1-AP

Synonyms

IL 17 receptor E, IL 17RE, IL17RE, IL-17RE, interleukin 17 receptor E

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Validation Data Gallery

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  WB analysis of human kidney using 11984-1-AP

  human kidney tissue were subjected to SDS PAGE followed by western blot with 11984-1-AP (IL17RE antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

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  WB analysis of PC-3 using 11984-1-AP

  PC-3 cells were subjected to SDS PAGE followed by western blot with 11984-1-AP (IL17RE antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

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  IHC staining of human pancreas cancer using 11984-1-AP

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer using 11984-1-AP (IL17RE antibody) at dilution of 1:50 (under 10x lens).

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Tested Applications

• Positive WB detected in: human kidney tissue, PC-3 cells
• Positive IHC detected in: human pancreas cancer tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000
• Immunohistochemistry (IHC): IHC : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below
• IHC: See 1 publications below
• IF: See 1 publications below

Product Information

11984-1-AP targets IL-17RE in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Cited Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: IL-17RE fusion protein Ag2612
• Full Name: interleukin 17 receptor E
• Calculated Molecular Weight: 667 aa, 75 kDa
• Observed Molecular Weight: 75 kDa, 58 kDa
• GenBank Accession Number: BC063110
• Gene Symbol: IL-17RE
• Gene ID (NCBI): 132014
• RRID: AB_878037
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

IL17RE, is a specific functional receptor for IL17C. It may be signaling through the NF-kappa-B and MAPK pathways. IL17Re may be a crucial regulator in innate immunity to bacterial pathogens. IL17RE has five isoforms with MW 31 kDa, 43 kDa, 58-62 kDa and 75 kDa.

Publications

Species	Application	Title
human,mouse	IHC,IF	Int Immunopharmacol; Clinical significance of Interleukin 17 receptor E in diabetic nephropathy; Authors - Jingjing Wang
human	WB	Am J Respir Cell Mol Biol; IL-17C is a mediator of respiratory epithelial innate immune response.; Authors - Pfeifer Philipp P