IL-17RE Polyclonal antibody

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• IL-17RE Polyclonal antibody (11984-1-AP)

IL-17RE Polyclonal Antibody for WB, IHC, ELISA

Cat No. 11984-1-AP Copied!

Publications (4)

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Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IF, ELISA

Synonyms

IL 17 receptor E, IL 17RE, IL17RE, IL-17RE, interleukin 17 receptor E

• 

  WB analysis of human kidney using 11984-1-AP

  human kidney tissue were subjected to SDS PAGE followed by western blot with 11984-1-AP (IL17RE antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of PC-3 using 11984-1-AP

  PC-3 cells were subjected to SDS PAGE followed by western blot with 11984-1-AP (IL17RE antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IHC staining of human pancreas cancer using 11984-1-AP

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer using 11984-1-AP (IL17RE antibody) at dilution of 1:50 (under 10x lens).

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: human kidney tissue, PC-3 cells
• Positive IHC detected in: human pancreas cancer tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000
• Immunohistochemistry (IHC): IHC : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

11984-1-AP targets IL-17RE in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Cited Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag2612

  Product name: Recombinant human IL-17RE protein

  Source: e coli.-derived, PKG

  Tag: GST

  Domain: 1-271 aa of BC063110

  Sequence: MGSSRLAALLLPLLLIVIDLSDSAGIGFRHLPHWNTRCPLASHTDDSFTGSSAYIPCRTWWALFSTKPWCVRVWHCSRCLCQHLLSGGSGLQRGLFHLLVQKSKKSSTFKFYRRHKMPAPAQRKLLPRRHLSEKSHHISIPSPDISHKGLRSKRTQPSDPETWESLPRLDSQRHGGPEFSFDLLPEARAIRVTISSGPEVSVRLCHQWALECEELSSPYDVQKIVSGGHTVELPYEFLLPCLCIEASYLQEDTVRRKKCPFQSWPEACECC

• Full Name: interleukin 17 receptor E
• Calculated Molecular Weight: 667 aa, 75 kDa
• Observed Molecular Weight: 75 kDa, 58 kDa
• GenBank Accession Number: BC063110
• Gene Symbol: IL-17RE
• Gene ID (NCBI): 132014
• RRID: AB_878037
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q8NFR9
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

IL17RE, is a specific functional receptor for IL17C. It may be signaling through the NF-kappa-B and MAPK pathways. IL17Re may be a crucial regulator in innate immunity to bacterial pathogens. IL17RE has five isoforms with MW 31 kDa, 43 kDa, 58-62 kDa and 75 kDa.

Publications

What published studies show

Antibody: Anti-IL-17C (Catalog No. 11984-1-AP) has 4 total citations published in Cell Reports in Medicine, International Immunopharmacology, American Journal of Respiratory Cell and Molecular Biology, and Molecular Immunology. Research fields span endometriosis carcinogenesis, diabetic nephropathy, respiratory epithelial innate immunity, and psoriasis/keratinocyte biology. Applications include WB, IHC, and IF in human and mouse samples.

Automatically generated from the 4 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
	WB,IHC,IF	Cell Rep Med; Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis; Authors - Bo Yao
human,mouse	IHC,IF	Int Immunopharmacol; Clinical significance of Interleukin 17 receptor E in diabetic nephropathy; Authors - Jingjing Wang
human	WB	Am J Respir Cell Mol Biol; IL-17C is a mediator of respiratory epithelial innate immune response.; Authors - Pfeifer Philipp P
human	IF	Mol Immunol; Promoting keratinocyte psoriasiform changes and IL-17RE expression: Potential role of GLT1D1 in linear psoriasis.; Authors - Yufan Cheng