Product Information
17995-1-AP targets IL-29 in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | IL-29 fusion protein Ag12444 Predict reactive species |
| Full Name | interleukin 29 (interferon, lambda 1) |
| Calculated Molecular Weight | 200 aa, 22 kDa |
| GenBank Accession Number | BC074985 |
| Gene Symbol | IL-29 |
| Gene ID (NCBI) | 282618 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8IU54 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Interleukin-29 (IL-29) is a member of the helical cytokine family and is a type III interferon. It is also known as IFNλ1 and is highly similar in amino acid sequence to the IL-28, the other type III interferon. It is produced predominantly by maturing dendritic cells and macrophages. It has been implicated in numerous immunological responses and has shown antiviral activity similar to the Type I interferons.Multiple studies also indicate IL-29's involvement in the pathogenesis of cancer, as well as its antitumor effects.
Publications
| Species | Application | Title |
|---|---|---|
J Immunol HERP Binds TBK1 To Activate Innate Immunity and Repress Virus Replication in Response to Endoplasmic Reticulum Stress. |
