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Anti-Human ILT-3/LILRB4 Rabbit Recombinant Antibody, PBS Only (98486-3-PBS)

Anti-Human ILT-3/LILRB4 Rabbit Recombinant Antibody, PBS Only

Name: Anti-Human ILT-3/LILRB4 Rabbit Recombinant Antibody, PBS Only, 1mg
Brand: Proteintech
SKU: 98486-3-PBS-1MG

ILT-3/LILRB4 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98486-3-PBS

Clone No.250356B3

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Synonyms

LILRB4, B4, CD85 antigen-like family member K, CD85k, ILT3

Formulation: PBS Only

PBS, Azide

PBS Only

Conjugate: Unconjugated

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Filter: AllFC

FC experiment of human PBMCs using 98486-3-RR (same clone as 98486-3-PBS)
1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ILT-3/LILRB4 Rabbit RecAb (98486-3-RR, Clone: 250356B3) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L).Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98486-3-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
×
1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ILT-3/LILRB4 Rabbit RecAb (98486-3-RR, Clone: 250356B3) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L).Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98486-3-PBS in a different storage buffer formulation.
FC experiment of human PBMCs using 98486-3-RR (same clone as 98486-3-PBS)
1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ILT-3/LILRB4 Rabbit RecAb (98486-3-RR, Clone: 250356B3) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98486-3-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
×
1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ILT-3/LILRB4 Rabbit RecAb (98486-3-RR, Clone: 250356B3) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98486-3-PBS in a different storage buffer formulation.

Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

98486-3-PBS targets ILT-3/LILRB4 in FC applications and shows reactivity with human samples.

Tested Reactivity	human
Host / Isotype	Rabbit / IgG
Class	Recombinant
Type	Antibody
Immunogen	CatNo: Eg1743 Product name: Recombinant Human ILT-3/LILRB4 protein (rFc Tag) Source: mammalian cells-derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 22-259 aa of AAH26309.1 Sequence: QAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEESPAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMTGAYSKPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEGPRPSPTRSVSTAAGPEDQPLMPTGSVPHSGLRRHWE Predict reactive species
Full Name	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
Calculated Molecular Weight	49kDa
GenBank Accession Number	AAH26309.1
Gene Symbol	LILRB4
Gene ID (NCBI)	11006
RRID	AB_3746116
Conjugate	Unconjugated
Form	Liquid
Purification Method	Protein A purification
UNIPROT ID	Q8NHJ6
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

LILRB4 is an inhibitory receptor in the LILR family mainly expressed on normal and malignant human cells of myeloid origin. LILRB4 is activated and subsequently recruits adaptors to cytoplasmic immunoreceptor tyrosine inhibitory motifs to initiate different signaling cascades, thus playing an important role in physiological and pathological conditions, including autoimmune diseases, microbial infections, and cancers.