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- KD/KO Validated
IMMT Monoclonal antibody, PBS Only
IMMT Monoclonal Antibody for WB, IF, FC, IHC, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
Human, Rat, Mouse
Applications
WB, IF, FC, IHC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2D2E8
Cat no : 68226-1-PBS
Synonyms
Validation Data Gallery
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
68226-1-PBS targets IMMT in WB, IF, FC, IHC, Indirect ELISA applications and shows reactivity with Human, Rat, Mouse samples.
Tested Reactivity | Human, Rat, Mouse |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | IMMT fusion protein Ag0102 |
Full Name | inner membrane protein, mitochondrial (mitofilin) |
Calculated Molecular Weight | 90 kDa |
Observed Molecular Weight | 90 kDa |
GenBank Accession Number | BC002412 |
Gene Symbol | IMMT |
Gene ID (NCBI) | 10989 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
IMMT (also known as mitofilin) is an inner mitochondrial membrane protein that is preferentially expressed in heart tissue and is commonly used as the marker for mitochondria. Mitofilin is known to be a critical organizer of mitochondrial cristae morphology and is indispensable for normal mitochondrial function. Three isoforms of mitofilin exist due to the alternative splicing. All three proteins of 87kD, 89kD and 80kD can be detected in immunoblot analysis with this antibody.