INTS8 Polyclonal antibody, PBS Only

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• INTS8 Polyclonal antibody, PBS Only (18802-1-PBS)

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  WB analysis of MCF-7 using 18802-1-AP (same clone as 18802-1-PBS)

  MCF7 cells were subjected to SDS PAGE followed by western blot with 18802-1-AP (INTS8 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18802-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 18802-1-AP (same clone as 18802-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 18802-1-AP (INTS8 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18802-1-PBS in a different storage buffer formulation.

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  IP experiment of HeLa using 18802-1-AP (same clone as 18802-1-PBS)

  IP result of anti-INTS8 (IP:18802-1-AP, 4ug; Detection:18802-1-AP 1:500) with HeLa cells lysate 4000ug. This data was developed using the same antibody clone with 18802-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 18802-1-AP (same clone as 18802-1-PBS)

  Immunofluorescent analysis of Hela cells, using INTS8 antibody 18802-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). This data was developed using the same antibody clone with 18802-1-PBS in a different storage buffer formulation.

INTS8 Polyclonal Antibody for WB, IF/ICC, IP, Indirect ELISA

Cat No. 18802-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, IP, Indirect ELISA

Synonyms

Protein kaonashi-1, Protein kaonashi 1, Integrator complex subunit 8, Int8, C8orf52

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Product Information

18802-1-PBS targets INTS8 in WB, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: integrator complex subunit 8
• Calculated Molecular Weight: 111 kDa
• Observed Molecular Weight: 95-111 kDa
• GenBank Accession Number: BC136754
• Gene Symbol: INTS8
• Gene ID (NCBI): 55656
• RRID: AB_10597250
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q75QN2
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Integrator complex subunit 8 (INTS8) is one of the major components of RNA polymerase II and has been demonstrated to be involved in the cleavage of small nuclear RNAs and transcriptional processes (PMID: 34880328). INTS8 was robustly increased in neurodevelopmental diseases and numerous tumors. High INTS8 expression has a tight correlation with poor prognosis in multi-cancers (PMID: 30881114). Western blot analysis detected INTS8 at an apparent molecular mass of 111 kDa.