IRF6 Polyclonal antibody

IRF6 Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 12928-1-AP


interferon regulatory factor 6, IRF 6, IRF6, LPS, OFC6, PIT, PPS, VWS

Tested Applications

Positive WB detected inA431 cells, A549 cells, HaCaT cells
Positive IHC detected inhuman lung tissue, mouse kidney tissue, human stomach cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:1000-1:4000
Immunohistochemistry (IHC)IHC : 1:250-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

12928-1-AP targets IRF6 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen IRF6 fusion protein Ag3623
Full Name interferon regulatory factor 6
Calculated Molecular Weight 467 aa, 53 kDa
Observed Molecular Weight53-60 kDa
GenBank Accession NumberBC014852
Gene Symbol IRF6
Gene ID (NCBI) 3664
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The interferon regulatory factor (IRF) family of genes directs the expression and activity of interferon and thus can strictly regulate innate immunity. Interferon regulatory factor 6 (IRF6) belongs to a family of nine transcription factors that share a highly conserved helix−turn−helix DNA-binding domain and a less conserved protein-binding domain. IRF6 regulates the balance between immature ectoderm differentiation and proliferation during craniofacial morphogenesis. IRF6 functions as a tumor suppressor gene in breast cancer, cervical cancer, nasopharyngeal carcinoma and so on.


Product Specific Protocols
WB protocol for IRF6 antibody 12928-1-APDownload protocol
IHC protocol for IRF6 antibody 12928-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols