Product Information
20324-1-PBS targets ISCA1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag14188 Product name: Recombinant human ISCA1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-129 aa of BC002675 Sequence: MSASLVRATVRAVSKRKLQPTRAALTLTPSAVNKIKQLLKDKPEHVGVKVGVRTRGCNGLSYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYVEDKLSSEFVFNNPNIKGTCGCGESFNI Predict reactive species |
| Full Name | iron-sulfur cluster assembly 1 homolog (S. cerevisiae) |
| Calculated Molecular Weight | 129 aa, 14 kDa |
| Observed Molecular Weight | 15 kDa |
| GenBank Accession Number | BC002675 |
| Gene Symbol | ISCA1 |
| Gene ID (NCBI) | 81689 |
| RRID | AB_3741988 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9BUE6 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
ISCA1, also named as HBLD2 and hIscA, belongs to the hesB/iscA family. It is involved in the assembly of mitochondrial iron-sulfur proteins. ISCA1 probably involved in the binding of an intermediate of Fe/S cluster assembly. ISCA1 plays an important role in both mitochondrial and cytosolic iron-sulfur cluster biogenesis, and a notable component of the latter is the interaction between ISCA1 and IOP1.
