ITGA6X1A Polyclonal antibody

ITGA6X1A Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB,ELISA

Conjugate

Unconjugated

Cat no : 20231-1-AP

Synonyms

CD49f, Integrin alpha 6, integrin, alpha 6, ITGA6, ITGA6B, VLA 6



Tested Applications

Positive WB detected inmouse spleen tissue, mouse colon tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
Sample-dependent, check data in validation data gallery

Product Information

20231-1-AP targets ITGA6X1A in WB,ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name integrin, alpha 6
Calculated molecular weight 127 kDa
Observed molecular weight 100 kDa, 150 kDa
GenBank accession numberNM_000210
Gene symbol ITGA6
Gene ID (NCBI) 3655
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ITGA6, also named as CD49f and VLA-6, belongs to the integrin alpha chain family. It is a receptor for laminin on platelets. ITGA6 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia (EB-PA) which also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. The antibody is specific to isoform Alpha-6X1A, isoform Alpha-6X2A, isoform Alpha-6X1X2A isoform7 and isoform9 of ITGA6.

Protocols

Product Specific Protocols
WB protocol for ITGA6X1A antibody 20231-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols