ITPRIP Recombinant monoclonal antibody

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• ITPRIP Recombinant monoclonal antibody (88074-2-RR)

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  WB analysis using 88074-2-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 88074-2-RR (ITPRIP antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

ITPRIP Uni-rAb^® Recombinant Antibody for WB, ELISA

Cat No. 88074-2-RR

Clone No.260374A2

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

bA127L20, DANGER, Inositol 1,4,5-trisphosphate receptor-interacting protein, KIAA1754, Protein DANGER

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Tested Applications

• Positive WB detected in: HeLa cells, MDA-MB-453 cells, U-87 MG cells

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

88074-2-RR targets ITPRIP in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Eg5612

  Product name: Recombinant human ITPRIP protein

  Source: mammalian cells-derived, V37

  Tag: C-rFc

  Domain: 16-83 aa of NM_001272012.2

  Sequence: IINHPLLFPRENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETR

• Full Name: inositol 1,4,5-triphosphate receptor interacting protein
• Calculated Molecular Weight: 62 kDa
• Observed Molecular Weight: 62 kDa
• GenBank Accession Number: NM_001272012.2
• Gene Symbol: ITPRIP
• Gene ID (NCBI): 85450
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q8IWB1
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ITPRIP (inositol 1,4,5-trisphosphate receptor interacting protein) is a key regulatory protein that binds to IP3 receptors to modulate endoplasmic reticulum calcium release and intracellular calcium homeostasis. It is widely expressed in human tissues with high abundance in the central nervous system. ITPRIP participates in neurodevelopment, cell apoptosis, innate immunity and tumor progression. Its abnormal expression is closely linked to glioma malignancy, neurodevelopmental disorders and immune dysfunction, serving as an essential molecule in physiological regulation and disease pathogenesis. (PMID: 29899107)