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Anti-Human Integrin alpha V Rabbit Recombinant Antibody, PBS Only (98996-1-PBS)

Anti-Human Integrin alpha V Rabbit Recombinant Antibody, PBS Only

Name: Anti-Human Integrin alpha V Rabbit Recombinant Antibody, PBS Only, 1mg
Brand: Proteintech
SKU: 98996-1-PBS-1MG

Integrin alpha V Uni-rAb^® Recombinant Antibody for FC

Cat No. 98996-1-PBS

Clone No.261824A1

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Synonyms

ITGAV, CD51, Integrin alpha-V, Integrin alpha-V heavy chain, Integrin alpha-V light chain

Formulation: PBS Only

PBS, Azide

PBS Only

Conjugate: Unconjugated

Size/Concentration:

SKU:

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Freight/Packing: -

Quantity

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Proteintech Guarantee

Filter: AllFC

FC experiment of HT-1080 using 98996-1-RR (same clone as 98996-1-PBS)
1x10^6 HT-1080 cells were surface stained with 0.25 ug Anti-Human Integrin alpha V Rabbit RecAb (98996-1-RR, Clone: 261824A1) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and CoraLite647-conjugated F(ab')2 Fragment Donkey Anti-Rabbit IgG (H+L) (SA00014-7). Cells were not fixed. This data was developed using the same antibody clone with 98996-1-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
×
1x10^6 HT-1080 cells were surface stained with 0.25 ug Anti-Human Integrin alpha V Rabbit RecAb (98996-1-RR, Clone: 261824A1) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and CoraLite647-conjugated F(ab')2 Fragment Donkey Anti-Rabbit IgG (H+L) (SA00014-7). Cells were not fixed. This data was developed using the same antibody clone with 98996-1-PBS in a different storage buffer formulation.
FC experiment of MCF-7 using 98996-1-RR (same clone as 98996-1-PBS)
1x10^6 MCF-7 cells were surface stained with 0.25 ug Anti-Human Integrin alpha V Rabbit RecAb (98996-1-RR, Clone: 261824A1) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and CoraLite647-conjugated F(ab')2 Fragment Donkey Anti-Rabbit IgG (H+L) (SA00014-7). Cells were not fixed. This data was developed using the same antibody clone with 98996-1-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
×
1x10^6 MCF-7 cells were surface stained with 0.25 ug Anti-Human Integrin alpha V Rabbit RecAb (98996-1-RR, Clone: 261824A1) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and CoraLite647-conjugated F(ab')2 Fragment Donkey Anti-Rabbit IgG (H+L) (SA00014-7). Cells were not fixed. This data was developed using the same antibody clone with 98996-1-PBS in a different storage buffer formulation.
FC experiment of human peripheral blood platelets using 98996-1-RR (same clone as 98996-1-PBS)
1x10^6 human peripheral blood platelets were surface stained with 0.25 ug Anti-Human Integrin alpha V Rabbit RecAb (98996-1-RR, Clone: 261824A1) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and CoraLite®647-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98996-1-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
×
1x10^6 human peripheral blood platelets were surface stained with 0.25 ug Anti-Human Integrin alpha V Rabbit RecAb (98996-1-RR, Clone: 261824A1) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and CoraLite®647-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98996-1-PBS in a different storage buffer formulation.

Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

98996-1-PBS targets Integrin alpha V in FC applications and shows reactivity with human samples.

Tested Reactivity	human
Host / Isotype	Rabbit / IgG
Class	Recombinant
Type	Antibody
Immunogen	unknow Predict reactive species
Full Name	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
Gene Symbol	Integrin alpha V
Gene ID (NCBI)	3685
Conjugate	Unconjugated
Form	Liquid
Purification Method	Protein A purification
UNIPROT ID	P06756
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin alpha V, also known as CD51, is a type I transmembrane glycoprotein composed of an extracellular domain, a transmembrane region and cytoplasmic domain (PMID: 2430295; 1690718). It can form heterodimers with one of the five beta integrin subunits (beta 1, 3, 5, 6, 8) that recognize ligands containing the sequence Arg-Gly-Asp, such as vitronectin, fibronectin, and osteopontin (PMID: 37087799). Integrin alpha V mainly plays a role in extracellular matrix-mediated cell adhesion and migration, differentiation, wound healing, inflammation, tumorigenesis, proliferation, angiogenesis, and metastasis.