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Anti-Mouse JAM3 Rabbit Recombinant Antibody, PBS Only (98393-2-PBS)

Anti-Mouse JAM3 Rabbit Recombinant Antibody, PBS Only

Name: Anti-Mouse JAM3 Rabbit Recombinant Antibody, PBS Only, 1mg
Brand: Proteintech
SKU: 98393-2-PBS-1MG

JAM3 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98393-2-PBS

Clone No. 242630E6

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Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

Synonyms

JAM-2, JAM-3, JAM-C, Junctional adhesion molecule 3, Junctional adhesion molecule C

Formulation: PBS Only

PBS, Azide

PBS Only

Conjugate: Unconjugated

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FC experiment of Transfected HEK-293T using 98393-2-RR (same clone as 98393-2-PBS)
1x10^6 HEK-293T cells or JAM3 Transfected HEK-293T cells were surface stained with 0.25 ug Anti-Mouse JAM3 Rabbit RecAb (98393-2-RR, Clone: 242630E6) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98393-2-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
FC experiment of Transfected HEK-293T using 98393-2-RR (same clone as 98393-2-PBS)
1x10^6 HEK-293T cells or JAM3 Transfected HEK-293T cells were surface stained with 0.25 ug Anti-Mouse JAM3 Rabbit RecAb (98393-2-RR, Clone: 242630E6) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98393-2-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
×
1x10^6 HEK-293T cells or JAM3 Transfected HEK-293T cells were surface stained with 0.25 ug Anti-Mouse JAM3 Rabbit RecAb (98393-2-RR, Clone: 242630E6) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98393-2-PBS in a different storage buffer formulation.

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Tested Applications
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Product Information

98393-2-PBS targets JAM3 in FC applications and shows reactivity with mouse samples.

Tested Reactivity	mouse
Host / Isotype	Rabbit / IgG
Class	Recombinant
Type	Antibody
Immunogen	CatNo: Eg2661 Product name: Recombinant Mouse JAM-3 protein (rFc Tag)(HPLC verified) Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 30-241 aa of NM_023277.4 Sequence: EAVNLKSSNRNPVVHEFESVELSCIITDSQTSDPRIEWKKIQDGQTTYVYFDNKIQGDLAGRTDVFGKTSLRIWNVTRSDSAIYRCEVVALNDRKEVDEITIELIVQVKPVTPVCRIPAAVPVGKTATLQCQESEGYPRPHYSWYRNDVPLPTDSRANPRFQNSSFHVNSETGTLVFNAVHKDDSGQYYCIASNDAGAARCEGQDMEVYDLN Predict reactive species
Full Name	junction adhesion molecule 3
Calculated Molecular Weight	35 kDa
GenBank Accession Number	NM_023277.4
Gene Symbol	Jam3
Gene ID (NCBI)	83964
RRID	AB_3746038
Conjugate	Unconjugated
Form	Liquid
Purification Method	Protein A purification
UNIPROT ID	Q9D8B7
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

Junctional adhesion molecule 3 (JAM3) is a type I transmembrane glycoprotein containing two Ig-like domains, which is expressed in various tissues and plays a crucial role in cell junctions, cell polarity, and motility (PMID: 34292449; 28931565). It has been proposed that JAM3 participates in leukocyte-platelet interactions, as well as angiogenesis and brain development (PMID: 12208882; 23255084). JAM3 may also be a new marker for predicting the prognosis and immune functions of bladder cancer patients (PMID: 38400838).