KCND3 Recombinant monoclonal antibody, PBS Only

• 

  WB analysis of rat brain using 83640-5-RR (same clone as 83640-5-PBS)

  rat brain tissue were subjected to SDS PAGE followed by western blot with 83640-5-RR (KCND3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83640-5-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 83640-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83640-5-RR against Human KCND3 were performed. The affinity constant is 0.712 nM.

KCND3 Uni-rAb^® Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Cat No. 83640-5-PBS

Clone No.240578F12

Host / Isotype

Rabbit / IgG

Reactivity

human, rat

Applications

WB, Cytometric bead array, Indirect ELISA

Synonyms

240578F12, KCND3L, KCND3S, KSHIVB, KV4.3

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Product Information

83640-5-PBS targets KCND3 in WB, Cytometric bead array, Indirect ELISA applications and shows reactivity with human, rat samples.

• Tested Reactivity: human, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag22183

  Product name: Recombinant human KCND3 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 602-636 aa of BC113477

  Sequence: PALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL

• Full Name: potassium voltage-gated channel, Shal-related subfamily, member 3
• Calculated Molecular Weight: 655 aa, 73 kDa
• GenBank Accession Number: BC113477
• Gene Symbol: KCND3
• Gene ID (NCBI): 3752
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9UK17
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

KCND3 gene encodes the voltage-gated potassium ion channel subfamily D member 3, a six trans-membrane protein (Kv4.3), involved in the transient outward K+ current. KCND3 gene defect causes both cardiological and neurological syndromes. Kv4.3 contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.